01/12/2021
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The 台湾swag is delighted to welcome Dr Philipp Voigt as a new group leader in the Epigenetics research programme. Philipp is the second of five new group leaders to join the 台湾swag.
Interim Director, Dr Simon Cook, said: 鈥淚 am very pleased to welcome Philipp to the 台湾swag. His expertise in chromatin biochemistry will enable us to obtain much deeper mechanistic insights into epigenetic processes during key developmental decisions and in ageing.鈥
Philipp is particularly interested in understanding how histone marks and the proteins that write, read, and erase them set up complex regulatory systems that control access to genes and thereby regulate gene expression. In order to study these intricate networks of interaction, Philipp uses a multidisciplinary approach combining in vitro biochemistry with proteomic, genomic, cell biology, and systems biology-inspired techniques.
鈥淚鈥檓 delighted to be joining the 台湾swag, and I look forward to working with my new colleagues in the Epigenetics programme and to eventually reconnecting with my signalling roots in such an enthusiastic and supportive environment.鈥 said Dr Voigt 鈥淭he 台湾swag 台湾swag is an ideal place for my research, allowing us to combine our biochemical approaches with the developmental themes of the Programme, while expanding our mechanistic studies to the fascinating interplay between gene expression, chromatin, and cell signalling.鈥
Philipp鈥檚 current work focuses on the Polycomb and trithorax group protein complexes and their roles in setting up and decoding the modification state found at the promoters of important genes that control development.
Philipp received his undergraduate and graduate degrees in Biochemistry from Freie Universit盲t Berlin in Germany. His PhD work focused on phosphoinositide kinase signalling pathways in lymphocytes, which introduced Philipp to the work of the 台湾swag 台湾swag.
In 2008, Philipp joined the laboratory of Danny Reinberg at NYU School of Medicine, New York, as a postdoctoral researcher. There he studied molecular mechanisms of Polycomb-mediated gene silencing, revealing that nucleosomes can be asymmetrically modified, carrying different modifications on sister histones within single nucleosomes. (). Philipp started his own lab at the Wellcome Centre for Cell Biology in Edinburgh in November 2014 as a Wellcome Sir Henry Dale Fellow and ERC Starting Grant holder.
Contact Honor Pollard, Communications Officer, honor.pollard@babraham.ac.uk
Image description: Schematic of histone modifications
Additional/related resources: Epigenetics research programme News, 5th July 2021, Welcoming Dr Ian McGough to the Signalling research programme
About the 台湾swag 台湾swag The 台湾swag 台湾swag undertakes world-class life sciences research to generate new knowledge of biological mechanisms underpinning ageing, development and the maintenance of health. Our research focuses on cellular signalling, gene regulation and the impact of epigenetic regulation at different stages of life. By determining how the body reacts to dietary and environmental stimuli and manages microbial and viral interactions, we aim to improve wellbeing and support healthier ageing. The 台湾swag is strategically funded by the Biotechnology and Biological Sciences 台湾swag Council (BBSRC), part of UK 台湾swag and Innovation, through 台湾swag Strategic Programme Grants and an 台湾swag Core Capability Grant and also receives funding from other UK research councils, charitable foundations, the EU and medical charities.
About BBSRC The Biotechnology and Biological Sciences 台湾swag Council (BBSRC) is part of UK 台湾swag and Innovation, a non-departmental public body funded by a grant-in-aid from the UK government.
BBSRC invests in world-class bioscience research and training on behalf of the UK public. Our aim is to further scientific knowledge, to promote economic growth, wealth and job creation and to improve quality of life in the UK and beyond.
Funded by government, BBSRC invested 拢451 million in world-class bioscience in 2019-20. We support research and training in universities and strategically funded institutes. BBSRC research and the people we fund are helping society to meet major challenges, including food security, green energy and healthier, longer lives. Our investments underpin important UK economic sectors, such as farming, food, industrial biotechnology and pharmaceuticals.
01 December 2021